***Updated at 8:16 a.m.
Birmingham's mayor is saying the two crew members aboard were killed. UPS has not confirmed the deaths.
A federal aviation official says a large UPS cargo plane has crashed near an airport in Birmingham, Ala.
Federal Aviation Administration spokeswoman Kathleen Bergen tells The Associated Press the A300 plane crashed on approach to the airport before dawn Wednesday.
Bergen says the plane was en route from Louisville, Ky., to Birmingham as UPS Flight 1354.
Toni Bast, a spokeswoman for Birmingham's airport authority, says the plane crashed on the outskirts of Birmingham-Shuttlesworth International Airport.
Bast says the area is outside the perimeter fence of the airport. She says the crash hasn't affected airport operations.
Neither Bergen nor Bast had any information on injuries.