Lindsey Lowe of Hendersonville is charge with two counts of first-degree murder.
He defense attorneys will argue the 26-year-old woman had some form of mental impairment when she delivered the twin boys in her bedroom at her parents’ home.
According to an affadavit, she admitted to police she suffocated the newborns so her parents, would did not know she was pregnant, would not hear their cries.
Lowe, who graduated from WKU in 2008, was engaged at the time, although paternity tests revealed her fiancé was not the father of the babies.
Lowe has been free on a quarter-million-dollar bond since the crime in September 2011. Prosecutors claim it was premeditated murder and are seeking a life sentence if Lowe is convicted. Jury selection begins Monday.