Authorities say 16 people in Hardin, Muhlenberg and Nelson counties have been charged with drug trafficking after a yearlong investigation.
The News-Enterprise reports that the probe, titled "Operation Pill Crusher," netted arrests of 14 residents of Elizabethtown and one New Haven resident.
A warrant was also served on an inmate at the Green River Correctional Complex in Central City.
All but one of those arrested June 28 was charged with trafficking in prescription medication. One man was charged with selling marijuana.
Officials said that the prescription drugs being illegally sold included morphine, hydrocodone and Oxycodone.
Ron Eckart, director of the Greater Hardin County Narcotics Task Force, said detectives served arrest warrants after spending two weeks pursuing indictments through a Hardin County grand jury.